C&EN

New CRISPR-based tool targets DNA secondary structures with sequence specificity

A graphic representation of a round, lumpy, blue protein and a single, comblike, purple strand of RNA interacting with a twisted, double, blue strand of DNA that separates where it meets the RNA. A ...
GitHub

Python rich client for visual protein Sequence to Structure Analysis (PySSA)

📣 Update details for version 1.3.0 📣 Please reinstall PySSA if your current version is 1.2.0 or older! Version 1.3.0 fixes the bug that every structure ...
pv magazine International

US energy offices folded into new structure at Department of Energy

The US DoE has released a new organizational chart that has removed groups focused on energy efficiency, renewable energy, and reducing carbon emissions. A new hierarchical chart posted on the DoE ...
C&EN

WatCon: A Python Tool for Analysis of Conserved Water Networks Across Protein Families

You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters ...
IEEE

HighMPNN: A Graph Neural Network Approach for Structure-Constrained Cyclic Peptide Sequence Design

Abstract: Cyclic peptides become attractive therapeutic candidates due to their diverse biological activities. However, existing deep learning-based sequence design models, such as ProteinMPNN, are ...
eLife

Interpretable protein-DNA interactions captured by structure-sequence optimization

This valuable work presents an interpretable protein-DNA Energy Associative (IDEA) model for predicting binding sites and affinities of DNA-binding proteins. While the method is convincing, it ...
C&EN

MYTHOS: A Python Interface for Surface Crystal Structure Prediction of Organic Semiconductors

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. We introduce a new computational approach for predicting organic crystalline ...
IEEE

Protein-Binding RNA Prediction Based on Integrated Sequence-Structure-Function Pre-Training

Abstract: RNA binding proteins (RBPs) play a crucial role in regulating biological functions through their interactions with specific RNAs, significantly impacting various life processes.
Singularity Hub

This Robot Swarm Can Flow Like Liquid and Support a Human’s Weight

With their bright blue bases, yellow gears, and exposed circuit tops, the 3D-printed robots look like a child’s toys. Yet as a roughly two-dozen-member collective, they can flow around obstacles ...
Microsoft

Toward deep learning sequence–structure co-generation for protein design

Deep generative models that learn from the distribution of natural protein sequences and structures may enable the design of new proteins with valuable functions. While the majority of today’s models ...
Science Daily

With generative AI, chemists quickly calculate 3D genomic structures

Chemists have found a new way to determine 3D genome structures, using generative AI, that can predict thousands of genome structures in minutes, making it much speedier than existing methods for ...
CNN

Tracking the damage and devastation from the Los Angeles wildfires in maps

Entire neighborhoods burned to the ground. Dozens of casualties after people either couldn’t leave, or chose not to flee their homes. The Los Angeles wildfires of 2025 have left incredible devastation ...